William Rowell

@williamrowell
San Francisco Bay Area
he / him

Biotechnology

Pythonista

Bioinformatician

Biologist

Academic Research

Data Science

First Generation College Graduate

Antiracist

Self-Taught

Speaker

Conference Attendee

Early Adopter

Customer Support

Data Engineering

Product Research

GitHub user

Failure

Shitposter

Science Communication

Data Visualization

Side Projects

Cat Dad

Bash

Biology

Dog Dad

Collaborative biological data scientist with over 20 years of research experience, including 7 years in genomics. Currently focused on variant calling applications and workflows for highly accurate long‐read sequencing data. Practical experience in genomics, human and model organism genetics, neurogenetics, and molecular biology.

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I'm open to

open source contributions,

partnering on side projects,

giving code reviews,

writing blog posts,

and proofreading.

Contact Me

Resume

Feb 2017 - Present

Senior Staff Scientist, Bioinformatics, Pacific Biosciences

Sep 2015 - Feb 2017

Scientific Programmer, Q2 Lab Solutions

Mar 2010 - Sep 2015

Research Specialist, Janelia Research Campus, Howard Hughes Medical Institute

Aug 2002 - Feb 2009

Graduate Student, University of California Berkeley

Portfolio

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Cheung WA, Rowell WJ, Farrow EG, Johnson AF, Hall RJ, Cohen ASA, Means J, Zion TN, Portik DM, Saunders CT, Koseva B, Bi C, Schwendinger-Schreck C, Yoo B, Johnston JJ, Gibson M, Thiffault I, Younger...

Baid G, Cook DE, Shafin K, Yun T, Llinares-López F, Berthet Q, Belyaeva A, Töpfer A, Wenger AM, Rowell WJ, Yang H, Kolesnikov A, Ammar W, Vert J-P, Vaswani A, McLean CY, Nattestad M, Chang P-C, Car...

Freed D, Rowell WJ, Wenger AM, Li Z. 2022. Sentieon DNAscope LongRead - A highly Accurate, Fast, and Efficient Pipeline for Germline Variant Calling from PacBio HiFi reads. bioRxiv. https://doi.org...

Wagner J, Olson ND, Harris L, Khan Z, Farek J, Mahmoud M, Stankovic A, Kovacevic V, Yoo B, Miller N, Rosenfeld JA, Ni B, Zarate S, Kirsche M, Aganezov S, Schatz MC, Narzisi G, Byrska-Bishop M, Clar...

Things I’ve built

Developed an automated workflow for alignment and variant detection of PacBio HiFi WGS using pbmm2, DeepVariant, and WhatsHap. williamrowell/hifi-deepvariant-snakemake

Developed an automated workflow for rare variant analysis for PacBio HiFi WGS. PacificBiosciences/pb-human-wgs-workflow-snakemake

Speaking engagements

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Rowell WJ, Peluso P, Harting J, Qian Y, Wenger AM, Hall RJ, Rank DR. Comprehensive Variant Detection in a Human Genome with PacBio High-Fidelity Reads. Cold Spring Harbor Biological Data Science Me...

Rowell WJ, Wenger AM, Kolesnikov A, Chang P-C, Carroll A, Hall RJ, Peluso P. Comprehensive variant detection in a human genome with highly accurate long reads. European Human Genetics Conference. J...

Rowell WJ, Chakraborty S, Baybayan P, Hall RJ. Detection and phasing of small variants in Genome in a Bottle samples with highly accurate long reads. American Society of Human Genetics Annual Meeti...

Rowell WJ, Wenger AM. A workflow for the comprehensive detection and prioritization of variants in human genomes with PacBio HiFi reads. Cold Spring Harbor Biological Data Science Meeting. November...

Videos

Rowell WJ, Wenger AM, Baid G, Nattestad M, Carroll A, Chang P-C. Accurate, comprehensive variant calling in difficult-to-map genes using HiFi reads. (video) American Society of Human Genetics Annua...

Articles and blogs

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Mehinovic E, Gray T, Campbell M, Ekholm J, Wenger AM, Rowell WJ, Grudo A, Grimwood J, Korlach J, Gurnett C, Constantino JN, Turner TN. 2022. Germline mosaicism of a missense variant in KCNC2 in a m...

Cohen ASA, Farrow EG, Abdelmoity AT, Alaimo JT, Amudhavalli SM, Anderson JT, Bansal L, Bartik L, Baybayan P, Belden B, Berrios CD, Biswell RL, Buczkowicz P, Buske O, Chakraborty S, Cheung WA, Coffm...

Wagner J, Olson ND, Harris L, McDaniel J, Cheng H, Fungtammasan A, Hwang Y-C, Gupta R, Wenger AM, Rowell WJ, Khan ZM, Farek J, Zhu Y, Pisupati A, Mahmoud M, Xiao C, Yoo B, Sahraeian SME, Miller DE,...

Namiki S, Ros IG, Morrow C, Rowell WJ, Card GM, Korff W, Dickinson MH. 2022. A population of descending neurons that regulates the flight motor of Drosophila. Curr Biology. https://doi.org/10.1016/...